Part:BBa_K4458013

Aryl Hydrocarbon Receptor Nuclear Translocator(ARNT)

"This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013]"

https://www.ncbi.nlm.nih.gov/gene/405#reference-sequences

Sequence and Features

Assembly Compatibility:

• 10
  INCOMPATIBLE WITH RFC[10]

  Illegal EcoRI site found at 86
  Illegal EcoRI site found at 1147
  Illegal EcoRI site found at 2284
  Illegal SpeI site found at 991
  Illegal PstI site found at 1805
  Illegal PstI site found at 2087
  
• 12
  INCOMPATIBLE WITH RFC[12]

  Illegal EcoRI site found at 86
  Illegal EcoRI site found at 1147
  Illegal EcoRI site found at 2284
  Illegal SpeI site found at 991
  Illegal PstI site found at 1805
  Illegal PstI site found at 2087
  
• 21
  INCOMPATIBLE WITH RFC[21]

  Illegal EcoRI site found at 86
  Illegal EcoRI site found at 1147
  Illegal EcoRI site found at 2284
  
• 23
  INCOMPATIBLE WITH RFC[23]

  Illegal EcoRI site found at 86
  Illegal EcoRI site found at 1147
  Illegal EcoRI site found at 2284
  Illegal SpeI site found at 991
  Illegal PstI site found at 1805
  Illegal PstI site found at 2087
  
• 25
  INCOMPATIBLE WITH RFC[25]

  Illegal EcoRI site found at 86
  Illegal EcoRI site found at 1147
  Illegal EcoRI site found at 2284
  Illegal SpeI site found at 991
  Illegal PstI site found at 1805
  Illegal PstI site found at 2087
  Illegal NgoMIV site found at 1740
  
• 1000
  COMPATIBLE WITH RFC[1000]